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Product Name
VPREB3 antibody
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Description
VPREB3 Rabbit Polyclonal antibody. Positive WB detected in human spleen tissue, human placenta tissue. Observed molecular weight by Western-blot: 46kd
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
8HS20 antibody; N27C7 2 antibody; pre B lymphOCyte 3 antibody; Pre B lymphOCyte protein 3 antibody; Protein VPreB3 antibody; VPREB3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of VPREB3 recombinant protein (Accession Number: NM_013378). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
human spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:116769(VPREB3 antibody) at dilution of 1:400
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Background
VPREB3 (formerly named 8HS20) is a protein that associates with mu chains in the endoplasmic reticulum of pre-B cell lines (PMID: 8491176; 22684248). VPREB3 is normally expressed by precursor B cells in bone marrow and by a subset of normal germinal center B cells in secondary lymphoid organs. It has been reported that VPREB3 expression is associated with B-cell tumors with c-MYC abnormalities (PMID: 20823132).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"