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Product Name
Mouse VCL/Vinculin (His Tag) recombinant protein
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Description
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion (By similarity).
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Protein name
Vinculin
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Protein short names
MVCL; MV; 9430097D22; CMD1W; CMH15; RP11-178G16.3; AW545629; HEL114; AI462105; AA571387
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Uniprot ID
Q64727
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Gene Name
Vcl
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse VCL (NP_033528.3) (Met1-Gln1066) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse VCL comprises 1077 amino acids and has a predicted molecular mass of 118.2 kDa. The apparent molecular mass of the protein is approximately 118 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Mouse VCL / Vinculin Protein (His Tag) SDS-PAGE
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