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Product Name
Human VLDLR (His Tag) recombinant protein
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Description
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
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Protein name
Very low-density lipoprotein receptor
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Protein short names
AI451093; FLJ35024; CAMRQ1; AW047288; AA408956; CHRMQ1; RP11-320E16.1; CARMQ1; VLDLRCH; VLDLR
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Uniprot ID
P98155
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Gene Name
VLDLR
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human VLDLR isoform alpha (NP_003374.3) extracellular domain (Met 1-Ser 797) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human VLDLR comprises 781 amino acids with a predicted molecular mass of 86 kDa. It migrates with the apparent molecular weight of 150 & 180 kDa due to different glycosylation in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human VLDLR / VLDL Receptor Protein (His Tag) SDS-PAGE
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