TYROBP Polyclonal Antibody

Cat.#: 162272

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Product Information

  • Product Name
    TYROBP Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to TYROBP
  • Tested applications
    WB
  • Species reactivity
    Mouse, Rat
  • Alternative names
    TYROBP antibody; DAP12 antibody; KARAP antibody; PLOSL antibody; TYRO protein tyrosine kinase-binding protein antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TYROBP (NP_003323.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - TYROBP Polyclonal Antibody

    Western blot - TYROBP Polyclonal Antibody

    Western blot analysis of extracts of mouse pancreas, using TYROBP antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

  • Background
    Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"