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Product Name
Recombinant TRY1 protein (His tag)
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Description
Recombinant Serine protease 1 (PRSS1) fragment (residues 24-247) from Homo sapiens, designed to encompass the full Peptidase S1 domain. This high-purity protein is ideal for investigating protease activity, substrate specificity, and enzymatic mechanisms in research applications.
Serine protease 1, also known as anionic trypsin I or beta-trypsin, is a secreted extracellular enzyme encoded by the PRSS1 gene in humans. It exhibits catalytic activity against synthetic substrates such as Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec, and Boc-Val-Pro-Arg-Mec, with the single-chain form demonstrating higher activity than the two-chain form. As a secreted protein localized to the extracellular space, it plays crucial roles in proteolytic processes and digestive functions. The provided fragment (24-247) retains the complete Peptidase S1 domain, enabling focused studies on its enzymatic properties and biological significance.
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Protein name
Serine protease 1
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Uniprot ID
P07477
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Gene Name
PRSS1; TRP1; TRY1; TRYP1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 24-247 aa (P07477) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 25.77 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 26 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"