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Product Name
Human CLN2 (His Tag) recombinant protein
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Description
Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity).
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Protein name
Tripeptidyl-peptidase 1
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Protein short names
LYSOSOMAL PEPSTATIN INSENSITIVE PROTEASE; GIG1; LPIC; TRIPEPTIDYL AMINOPEPTIDASE; TPP-I; CEROID-LIPOFUSCINOSIS; TRIPEPTIDYL-PEPTIDASE 1; CELL GROWTH-INHIBITING GENE 1 PROTEIN; CLN2; NEURONAL 2; LYSOSOMAL PEPSTATIN-INSENSITIVE PROTEASE; TRIPEPTIDYL PEPTIDASE-I; GROWTH-INHIBITING PROTEIN 1; TPP-1
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Uniprot ID
O14773
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Gene Name
TPP1; CLN2; GIG1; UNQ267/PRO304
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the pro form of human TPP1 (AAH14863.1) (Met 1-Pro 563) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human TPP1 (pro form) comprises 554 amino acids and has a predicted molecular mass of 60.7 kDa. The apparent molecular mass of rhTPP1 is approximately 60 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human TPP1 / CLN2 Protein (His Tag) SDS-PAGE
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