TRAPPC9/NIBP antibody

Cat.#: 116349

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Product Information

  • Product Name
    TRAPPC9/NIBP antibody
  • Documents
  • Description
    TRAPPC9/NIBP Rabbit Polyclonal antibody. Positive WB detected in SH-SY5Y cells, human brain tissue, mouse kidney tissue. Positive IHC detected in human heart tissue, human kidney tissue. Observed molecular weight by Western-blot: 56kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    IBP antibody; IKBKBBP antibody; KIAA1882 antibody; NIBP antibody; NIK and IKBKB binding protein antibody; TRAPPC9 antibody; TRS120 antibody; Tularik gene 1 protein antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_031466). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:116349(TRAPPC9 antibody) at dilution of 1:300

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:116349(TRAPPC9 antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human heart using Catalog No:116349(TRAPPC9 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human heart using Catalog No:116349(TRAPPC9 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human heart using Catalog No:116349(TRAPPC9 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human heart using Catalog No:116349(TRAPPC9 antibody) at dilution of 1:100 (under 40x lens)

  • Background
    TRAPPC9, also named NIK- and IKBKB-binding protein (NIBP), is involved in the NF-kappaB signaling pathway and directly interacts with IKK-beta and MAP3K14. TRAPPC9 functions as an activator of NF-kappa-B via increased phosphorylation of the IKK complex. TARPPC9 may also function in neuronal cells differentiation and defects in TRAPPC9 are the cause of mental retardation autosomal recessive type 13 (MRT13), which is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior. TARPPC9 is a component of the multisubunit TRAPP (transport protein particle) complex and it may play a role in vesicular transport from endoplasmic reticulum to Golgi.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"