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Product Name
Recombinant THIO2 protein (His tag)
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Description
Recombinant Probable thioredoxin-2 (trx-2) fragment from Caenorhabditis elegans, encompassing residues 37-145. This 109-amino acid construct includes the complete Thioredoxin functional domain, making it an ideal tool for investigating redox regulation, dithiol-disulfide exchange, and domain-specific mechanisms in cellular processes.
Probable thioredoxin-2, encoded by the trx-2 gene in Caenorhabditis elegans, is a redox-active protein that participates in various cellular redox reactions. Its function involves the reversible oxidation of its active center dithiol to a disulfide, enabling it to catalyze critical dithiol-disulfide exchange reactions. These activities are essential for maintaining cellular redox homeostasis, regulating protein function, and supporting antioxidant defense mechanisms. The provided fragment retains the complete Thioredoxin domain (residues 39-144), preserving the protein's core redox functionality for targeted biochemical and functional studies.
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Protein name
Probable thioredoxin-2
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Uniprot ID
Q17424
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Gene Name
trx-2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 37-145 aa (Q17424) were fused with 6His tag.
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Protein Species
Caenorhabditis elegans
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Molecular weight
Predictes a molecular mass of 13.40 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 15 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"