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Product Name
Recombinant TBG2 protein (His tag)
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Description
Recombinant Tubulin gamma-2 chain (Gamma-2-tubulin) from Drosophila melanogaster, encompassing amino acids 1-457, is a high-quality protein fragment engineered for stability and solubility. This product is ideal for investigating microtubule nucleation, spindle assembly, and centrosome organization in structural and biochemical studies.
Tubulin gamma-2 chain, encoded by the gammaTub37C gene, is a key component of microtubules and is primarily localized at microtubule organizing centers (MTOCs) such as centrosomes and spindle poles. It plays a critical role in nucleating microtubule assembly from the minus end and is essential for organizing centrosomes and assembling mitotic spindles in embryos. Additionally, it is required for oocyte activation, female meiotic spindle organization, and stabilizing the augmin complex on the meiotic spindle, underscoring its importance in cellular division and structural integrity.
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Protein name
Tubulin gamma-2 chain
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Uniprot ID
P42271
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Gene Name
gammaTub37C; Tub37CD; TubG2; TubG37C
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-457 aa (P42271) were fused with 6His tag.
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Sequence
1-457
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Protein Species
Drosophila melanogaster
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Molecular weight
Predictes a molecular mass of 52.96 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 53 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"