-
Product Name
Human CD8B / P37 / LEU2 (Fc Tag) recombinant protein
- Documents
-
Description
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.
-
Protein name
T-cell surface glycoprotein CD8 beta chain
-
Protein short names
T LYMPHOCYTE SURFACE GLYCOPROTEIN BETA CHAIN; BETA POLYPEPTIDE 1 (P37); T-CELL MEMBRANE GLYCOPROTEIN LY-3; CD8B; LEU2; LYT3; LYMPHOCYTE ANTIGEN 3; CD8 ANTIGEN; CD8B1; LY-3; P37; LY-C; T-CELL SURFACE GLYCOPROTEIN LYT-3; T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN; LY3; LYT-3
-
Uniprot ID
P10966
-
Gene Name
CD8B; CD8B1
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human CD8B isoform 1 (P10966-1) extracellular domain (Met 1-Pro 170) was fused with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human CD8B/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 390 amino acids and has a predicted molecular mass of 44 kDa. The apparent molecular mass of the reduced monomer is approximately 50 kDa in SDS-PAGE under reducing conditions.
-
Purity
> 93 % as determined by SDS-PAGE
-
Validations
Human CD8B / P37 / LEU2 Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"