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Human CD8a / Lyt2 (His Tag) recombinant protein

Cat.#: 500217

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Product Information

  • Product Name
    Human CD8a / Lyt2 (His Tag) recombinant protein
  • Documents
  • Description
    Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
  • Protein name
    T-cell surface glycoprotein CD8 alpha chain
  • Protein short names
    LY-B; LY-2; LEU2; MAL; P32; LY-35; LYT-2; CD8; BB154331; CD8A
  • Uniprot ID
    Q8TAW8
  • Gene Name
    CD8A; MAL
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain of human CD8A (NP_001759.3) (Met 1-Asp 182) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CD8A consists of 172 amino acids and predicts a molecular mass of 19 kDa. As a result of glycosylation, rh CD8A migrates as an approximately 28 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Activity
    1. Measured by its ability to bind biotinylated recombinant human B2M in a functional ELISA.
    2. Measured by its ability to bind biotinylated recombinant human FCGRT+B2M in a functional ELISA.
    3. Measured by its ability to bind biotinylated recombinant human LCK in a functional ELISA.
  • Validations

    Human CD8A / MAL Protein (His Tag) SDS-PAGE

    Human CD8A / MAL Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"