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Product Name
Recombinant STIP1 protein (His tag)
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Description
Recombinant Stress-induced-phosphoprotein 1 (CeSTI1) fragment (amino acids 1-320) from Caenorhabditis elegans, encompassing the complete STI1 domain. This high-purity protein is ideal for investigating gonad development, longevity regulation, thermotolerance mechanisms, and Hsp90 interactions in research applications.
Stress-induced-phosphoprotein 1 (CeSTI1), also known as Hsc70/Hsp90-organizing protein (Hop), is a key regulatory protein in Caenorhabditis elegans that plays critical roles in gonad development, longevity up-regulation, and thermotolerance enhancement. It functions by binding to daf-21/Hsp90 and inhibiting its ATPase activity, thereby modulating chaperone-mediated processes. The protein is localized primarily in the cytoplasm, with detection in early-stage embryos, indicating its importance in developmental biology and stress response pathways. The provided fragment (1-320) contains the complete STI1 functional domain, making it particularly valuable for domain-specific functional studies.
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Protein name
Stress-induced-phosphoprotein 1
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Uniprot ID
O16259
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Gene Name
sti-1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-320 aa (O16259) were fused with 6His tag.
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Protein Species
Caenorhabditis elegans
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Molecular weight
Predictes a molecular mass of 38.62 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 44 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"