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Product Name
Human STC2 (Fc Tag) recombinant protein
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Description
STC2 is a secreted, homodimeric glycoprotein which expressed in a wide variety of tissues. STC2 has an anti-hypocalcemic action on calcium and phosphate homeostasis. It may have autocrine or paracrine functions. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. STC2 has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. It may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis.
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Protein name
Stanniocalcin-2
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Protein short names
STC2L; STCRP; STANNIOCALCIN-RELATED PROTEIN; AW125853; STC2; MUSTC2; STC-RELATED PROTEIN; STC-2; STANNIOCALCIN 2; RP23-31D18.1
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Uniprot ID
O76061
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Gene Name
STC2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human STC2 (O76061) (Met1-Arg302) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human STC2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 519 amino acids and has a predicted molecular mass of 57.7 kDa. The apparent molecular mass of the protein is approximately 63 kDa in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human STC2 / Stanniocalcin 2 Protein (Fc Tag) SDS-PAGE
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