STAMP C16G2 peptide

STAMP C16G2 peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

H-TFFRLFNRSFTQALGKGGGKNLRIIRKGIHIIKKY-OH

H-Thr-Phe-Phe-Arg-Leu-Phe-Asn-Arg-Ser-Phe-Thr-Gln-Ala-Leu-Gly-Lys-Gly-Gly-Gly-Lys-Asn-Leu-Arg-Ile-Ile-Arg-Lys-Gly-Ile-His-Ile-Ile-Lys-Lys-Tyr-OH

35

95.25%

C₁₉₀H₃₀₉N₅₇O₄₃

4079.83

Synthetic

Powder

STAMP C16G2 consists of a region (C16, amino acids 1 through 16) specifically targeting S. mutans, a bacterial species playing a primary role in the onset of dental caries, attached by means of three glycine residues to a novispirin-derived AMP that represents the “killing” region (G2, amino acids 20 through 35). C16G2 has been demonstrated to specifically eliminate S. mutans, and not other oral streptococci, in both planktonic- and saliva-derived biofilms.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Batoni G, Maisetta G, Esin S. Therapeutic Potential of Antimicrobial Peptides in Polymicrobial Biofilm-Associated Infections. Int J Mol Sci. 2021 Jan 6;22(2):482. doi: 10.3390/ijms22020482. PMID: 33418930; PMCID: PMC7825036.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.