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Product Name
Recombinant SRTD3 protein (His tag)
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Description
Recombinant SERTA domain-containing protein 3 (SERTAD3) fragment (amino acids 1-196) encompassing the complete SERTA functional domain. This high-purity human protein serves as an essential research tool for investigating innate immunity mechanisms, viral suppression pathways, and transcriptional coactivation functions.
SERTA domain-containing protein 3 is a multifunctional human nuclear protein that plays critical roles in innate immunity and antiviral defense. As an interferon-stimulated protein, it suppresses viral infections through multiple mechanisms, including disruption of influenza virus RNA polymerase complex formation and promotion of Zika virus capsid protein degradation via the proteasomal pathway. The protein also functions as a strong transcriptional coactivator and contributes to TLR-induced immune responses. Located in the nucleus, SERTAD3 represents a key regulatory component in host defense systems against viral pathogens, making it a valuable target for immunological and virological research.
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Protein name
SERTA domain-containing protein 3
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Uniprot ID
Q9UJW9
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Gene Name
SERTAD3; RBT1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-196 aa (Q9UJW9) were fused with 6His tag.
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Sequence
1-196
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 23.42 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 25 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"