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  • SRP9 antibody
  • SRP9 antibody
  • SRP9 antibody

SRP9 antibody

Cat.#: 115595

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Special Price 239.0 USD

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Product Information

  • Product Name
    SRP9 antibody
  • Documents
  • Description
    SRP9 Rabbit Polyclonal antibody. Positive IP detected in HepG2 cells. Positive WB detected in HepG2 cells, A2780 cells, MCF7 cells, mouse colon tissue, SKOV-3 cells. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 10 kDa
  • Tested applications
    ELISA, WB, IHC, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    ALURBP antibody; SRP9 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of SRP9 recombinant protein (Accession Number: BC015094). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:115595(SRP9 antibody) at dilution of 1:1000

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:115595(SRP9 antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:115595(SRP9 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:115595(SRP9 antibody) at dilution of 1:100 (under 10x lens)

    IP Result of anti-SRP9 (IP:Catalog No:115595, 3ug; Detection:Catalog No:115595 1:500) with HepG2 cells lysate 3600ug.

    IP Result of anti-SRP9 (IP:Catalog No:115595, 3ug; Detection:Catalog No:115595 1:500) with HepG2 cells lysate 3600ug.

  • Background
    Signal recognition particle 9(SRP9) is component of the signal recognition particle (SRP), which is a ribonucleoprotein complex that mediates the targeting of proteins to the rough endoplasmic reticulum (ER). SRP9 form a heterodimer with SRP14, which involves in arrest of the elongation of the nescent chains during targeting to ensure efficient translocation of the preprotein.
  • References
    • Rho JH, Qin S, Wang JY, Roehrl MH. Proteomic expression analysis of surgical human colorectal cancer tissues: up-regulation of PSB7, PRDX1, and SRP9 and hypoxic adaptation in cancer. Journal of proteome research. 7(7):2959-72. 2008.
    • Piazzon N, Schlotter F, Lefebvre S. Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle. Nucleic acids research. 41(2):1255-72. 2013.
    • Hessel EV, de Wit M, Wolterink-Donselaar IG. Identification of Srp9 as a febrile seizure susceptibility gene. Annals of clinical and translational neurology. 1(4):239-50. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"