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Product Name
Recombinant SP7 protein (His tag)
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Description
Recombinant Human Transcription Factor Sp7 (Zinc Finger Protein Osterix) Fragment (aa 276-376) is a high-quality protein product designed for structural and biochemical studies. This 101-amino acid fragment was computationally selected for its stability and solubility, offering researchers a reliable tool to investigate the mechanisms of osteoblast differentiation and transcriptional regulation.
Transcription factor Sp7, also known as Zinc finger protein osterix, is a transcriptional activator essential for osteoblast differentiation. It functions by binding to SP1 and EKLF consensus sequences as well as other G/C-rich sequences, playing a critical role in bone formation and development. The protein is localized to the nucleus, where it regulates gene expression. This recombinant fragment provides a focused approach to study specific structural and functional aspects of this important transcription factor without the complexities of the full-length protein.
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Protein name
Transcription factor Sp7
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Uniprot ID
Q8TDD2
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Gene Name
SP7; OSX
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 276-376 aa (Q8TDD2) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 13.47 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 13 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"