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Recombinant SOX4 protein (His tag)

Recombinant SOX4 protein (His tag)

Cat.#: 537969

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Product Information

  • Product Name
    Recombinant SOX4 protein (His tag)
  • Documents
  • Description

    Recombinant Transcription factor SOX-4 fragment (amino acids 54-135) from Homo sapiens, designed for structural and biochemical studies. This stable, soluble fragment enables investigation of SOX-4's transcriptional activation mechanisms in a highly workable format.

    Transcription factor SOX-4 is a nuclear transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3'. It plays critical roles in immune cell development, particularly in the maturation of IL17A-producing Vgamma2-positive gamma-delta T-cells through regulation of RORC expression. Additionally, SOX-4 contributes to skeletal myoblast differentiation by promoting CALD1 gene expression. The protein localizes to the nucleus where it executes its transcriptional regulatory functions.

  • Protein name
    Transcription factor SOX-4
  • Uniprot ID
    Q06945
  • Gene Name
    SOX4
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 54-135 aa (Q06945) were fused with 6His tag.
  • Sequence 
    54-135
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 11.66 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 12 kDa band.
  • Purity
    >86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"