SNRPB Polyclonal Antibody
Polyclonal antibody to SNRPB
SNRPB antibody; CCMS antibody; COD antibody; SNRPB1 antibody; Sm-B/B' antibody; SmB/B' antibody; SmB/SmB' antibody; snRNP-B antibody; small nuclear ribonucleoprotein polypeptides B and B1 antibody
Antigen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SNRPB (NP_003082.1).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
WB 1:500 - 1:2000
Western blot - SNRPB Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SNRPB antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit .Exposure time: 180s.
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
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