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Product Name
Recombinant SIRT2 protein (His tag)
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Description
Recombinant Drosophila melanogaster Sirt2 (NAD-dependent protein deacetylase) fragment (residues 1-323) encompassing the complete deacetylase sirtuin-type functional domain. This high-purity protein is ideal for investigating deacetylase activity, lifespan regulation mechanisms, and sirtuin-related biochemical pathways.
Sirt2 is an NAD-dependent protein deacetylase that plays a crucial role in cellular regulation. Based on functional studies, this enzyme may be involved in the regulation of life span, making it a significant target for aging research and metabolic studies. The full-length protein's deacetylase activity, dependent on NAD cofactors, modifies target proteins to influence various biological processes. While subcellular localization data is not specified, Sirt2's conserved deacetylase function across species underscores its importance in fundamental biological mechanisms.
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Protein name
NAD-dependent protein deacetylase Sirt2
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Uniprot ID
Q9I7I7
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Gene Name
Sirt2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-323 aa (Q9I7I7) were fused with 6His tag.
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Protein Species
Drosophila melanogaster
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Molecular weight
Predictes a molecular mass of 38.20 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 39 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"