RRBP1 antibody

Cat.#: 114922

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Product Information

  • Product Name
    RRBP1 antibody
  • Documents
  • Description
    RRBP1 Rabbit Polyclonal antibody. Positive IF detected in NIH/3T3 cells. Positive IHC detected in human lung cancer tissue, human pancreas tissue. Positive WB detected in mouse pancreas tissue, NIH/3T3 cells. Observed molecular weight by Western-blot: 109 kDa
  • Tested applications
    ELISA, WB, IHC, IF
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    DKFZp586A1420 antibody; ES/130 antibody; ES/130 related protein antibody; ES130 antibody; FLJ36146 antibody; hES antibody; KIAA1398 antibody; Ribosome binding protein 1 antibody; Ribosome receptor protein antibody; RRBP1 antibody; RRp antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of RRBP1 recombinant protein (Accession Number: BC128577). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

    IF: 1:20-1:200

  • Validations

    mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:114922(RRBP1 antibody) at dilution of 1:800

    mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:114922(RRBP1 antibody) at dilution of 1:800

    Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using Catalog No:114922(RRBP1 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using Catalog No:114922(RRBP1 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using Catalog No:114922(RRBP1 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using Catalog No:114922(RRBP1 Antibody) at dilution of 1:50 (under 40x lens)

    Immunofluorescent analysis of NIH/3T3 cells using Catalog No:114922(RRBP1 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of NIH/3T3 cells using Catalog No:114922(RRBP1 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    Ribosome-binding protein 1 (RRBP1) is an endoplasmic reticulum membrane protein. It is a 1410 amino acid protein composed of a hydrophobic NH2-terminus that includes a transmembrane domain, a highly conserved tandem repeat (ribosome-binding domain), and an acidic coiled-coil COOH-terminal domain. RRBP1 acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane. It is also involved in early cardiac morphogenesis. (PMID: 22709790; 8812507; 7686155)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"