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  • RK-10, a specific PD-L1 binding peptide

RK-10, a specific PD-L1 binding peptide

Cat.#: 318728

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Special Price 222.20 USD

Availability: Discontinued
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Product Information

  • Product Name
    RK-10, a specific PD-L1 binding peptide
  • Documents
  • Quantity/Unit
    1 Vial
  • Sequence
    GSGSGSTYLCGAISLAPKAQIKESL
  • Three letter code
    H-Gly-Ser-Gly-Ser-Gly-Ser-Thr-Tyr-Leu-Cys-Gly-Ala-Ile-Ser-Leu-Ala-Pro-Lys-Ala-Gln-Ile-Lys-Glu-Ser-Leu-NH2
  • Length (aa)
    25
  • Peptide Purity (HPLC)
    95.2
  • Molecular Formula
    C105H177N29O35S1
  • Molecular Weight
    2437.78
  • Source
    Synthetic
  • Additional Information
    RK-10, a specific PD-L1 binding peptide, could be used for detecting PD-L1 expressing tumors with immunohistochemistry or flow cytometry. Flow cytometry was performed on cell lines and patient tissues using a fluorescent peptide (RK-10-Cy5). Immunohistochemistry using a biotin-modified peptide (RK-10-Biotin) was tested against the FDA-approved SP263 clone on biopsied patient tissues. RK-10 shows staining in the tumor regions of FFPE tissues where the SP263 kit does not. RK-10-Cy5 peptide also demonstrates PD-L1 detection in NSCLC, breast, squamous cell carcinoma, and melanoma.
  • Storage Guidelines
    Ideally RK-10, a specific PD-L1 binding peptide should be stored in a freezer at or below -9C. RK-10, a specific PD-L1 binding peptide should be refrigerated after reconstitution. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Caldwell, C., Johnson, C. E., Balaji, V. N., Balaji, G. A., Hammer, R. D., & Kannan, R. (2017). Identification and Validation of a PD-L1 Binding Peptide for Determination of PDL1 Expression in Tumors. Scientific Reports, 7(1).

Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"