Mouse SBDS / Shwachman-Bodian-Diamond syndrome (His Tag) recombinant protein

Cat.#: 501918

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Product Information

  • Product Name
    Mouse SBDS / Shwachman-Bodian-Diamond syndrome (His Tag) recombinant protein
  • Documents
  • Description
    Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity).
  • Protein name
    Ribosome maturation protein SBDS
  • Protein short names
    CGI-97; SDS; SHWACHMAN-BODIAN-DIAMOND SYNDROME HOMOLOG (HUMAN); AI836084; SHWACHMAN-BODIAN-DIAMOND SYNDROME; 4733401P19RIK; RIBOSOME MATURATION PROTEIN SBDS; SWDS; SBDS; PROTEIN 22A3; SHWACHMAN-BODIAN-DIAMOND SYNDROME PROTEIN HOMOLOG
  • Uniprot ID
    P70122
  • Gene Name
    Sbds
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse Sbds (NP_075737.1) (Met1-Glu250) was expressed with a polyhistidine tag at the N-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse Sbds consists 268 amino acids and predicts a molecular mass of 31 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Validations

    Mouse SBDS / Shwachman-Bodian-Diamond syndrome Protein (His Tag) SDS-PAGE

    Mouse SBDS / Shwachman-Bodian-Diamond syndrome Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"