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Human RCN3 (His Tag) recombinant protein

Cat.#: 503088

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Product Information

  • Product Name
    Human RCN3 (His Tag) recombinant protein
  • Documents
  • Description
    RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents the target sequence of subtilisin-like proprotein convertases(SPCs). SPCs are a family of seven structurally related serine endoproteases that are involved in the proteolytic activation of proproteins.RCN3 is transiently associated with proPACE4, but not with mature PACE4. Inhibition of PACE4 maturation by a Ca2+ ionophore resulted in accumulation of the proPACE4-RCN-3 complex in cells. It has been proposed that elective and transient association of RCN3 with the precursor of PACE4 plays an important role in the biosynthesis of PACE4.
  • Protein name
    Reticulocalbin-3
  • Protein short names
    UNQ239/PRO272; RETICULOCALBIN-3; EF-HAND CALCIUM-BINDING PROTEIN RLP49; D530026G20RIK; RETICULOCABIN; 6030455P07RIK; D7ERTD671E; RLP49
  • Uniprot ID
    Q96D15
  • Gene Name
    RCN3; UNQ239/PRO272
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human RCN3 (Q96D15) (Met1-His324) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human RCN3 comprises 315 amino acids and has a predicted molecular mass of 36.2 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions
  • Purity
    > 90 % as determined by SDS-PAGE
  • Validations

    Human RCN3 Protein (His Tag) SDS-PAGE

    Human RCN3 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"