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  • Ranalexin peptide

Ranalexin peptide

Not For Human Use, Lab Use Only.

Cat.#: 312701

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* Buy 1 get 1 free (?) What is TFA?

Special Price 363.00 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Ranalexin peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    FLGGLIKIVPAMICAVTKKC
  • Sequence
    H-Phe-Leu-Gly-Gly-Leu-Ile-Lys-Ile-Val-Pro-Ala-Met-Ile-Cys-Ala-Val-Thr-Lys-Lys-Cys-OH (Disulfide bond)
  • Length (aa)
    20
  • Peptide Purity (HPLC)
    97.1%
  • Molecular Formula
    C97H167N23O22S3
  • Molecular Weight
    2103.7
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Recombinant peptide is as active as the WT against S. aureus, S. pyogenes, E. coli, and MRSA (MIC 8 and 128 ug/ml). The recombinant ranalexin is also cytotoxic in HeLa and COS7 human cancer cells (IC50 =13-15 ug/ml)(Appl Microbiol Biotechnol. 2012). In membrane-mimetic TFE or DPC micelles, residues 8-15 are helical (edited 11/4/2007 GW). In an animal model:mouse for systemic infection, the peptide showed synergistic effect against MRSA with antistaphylococcal endopeptidase (Desbois AP et al., 2010 Int J Antimicrob Agents 35: 559-65). Updated 10/12/2012 GW. Ranalexin has Antibacterial, Antifungal activity. Ranalexin was found in Bull frog, Rana catesbeiana, North America.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-FLGGLIKIVPAMICAVTKKC-OH
  • Chemical Formula:C97H167N23O22S3
  • Sequence length:20
  • Extinction coefficient:120 M-1cm-1
  • GRAVY:1.4
  • Mw average:2103.69
  • Theoretical pI:9.8
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"