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  • RAB7A antibody
  • RAB7A antibody
  • RAB7A antibody
  • RAB7A antibody

RAB7A antibody

Cat.#: 114458

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Special Price 239.0 USD

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Product Information

  • Product Name
    RAB7A antibody
  • Documents
  • Description
    RAB7A Rabbit Polyclonal antibody. Positive IHC detected in human stomach tissue, human skeletal muscle tissue. Positive IP detected in SH-SY5Y cells. Positive WB detected in SH-SY5Y cells, A431 cells, C6 cells, mouse brain tissue, NIH/3T3 cells. Observed molecular weight by Western-blot: 23 kDa
  • Tested applications
    ELISA, WB, IHC, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    FLJ20819 antibody; PRO2706 antibody; RAB7 antibody; RAB7A antibody; Ras related protein Rab 7a antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_004637). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:114458(RAB7A antibody) at dilution of 1:800

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:114458(RAB7A antibody) at dilution of 1:800

    IP Result of anti-RAB7A (IP:Catalog No:114458, 4ug; Detection:Catalog No:114458 1:300) with SH-SY5Y cells lysate 1600ug.

    IP Result of anti-RAB7A (IP:Catalog No:114458, 4ug; Detection:Catalog No:114458 1:300) with SH-SY5Y cells lysate 1600ug.

    Immunohistochemistry of paraffin-embedded human stomach tissue slide using Catalog No:114458(RAB7A Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human stomach tissue slide using Catalog No:114458(RAB7A Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human stomach tissue slide using Catalog No:114458(RAB7A Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human stomach tissue slide using Catalog No:114458(RAB7A Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    RAB7A, also named as RAB7, belongs to the small GTPase superfamily and Rab family. It is involved in late endocytic transport. RAB7A contributes to the maturation of phagosomes (acidification). Defects in RAB7A are the cause of Charcot-Marie-Tooth disease type 2B (CMT2B). This antibody is specific to RAB7A.
  • References
    • Hu X, Yu J, Zhou X. Synergism between upregulation of Rab7 and inhibition of autophagic degradation caused by mycoplasma facilitates intracellular mycoplasma infection. Molecular medicine reports. 9(3):793-800. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"