NovoPro
Cart 2
  • RAB3IP/Rabin8 antibody
  • RAB3IP/Rabin8 antibody
  • RAB3IP/Rabin8 antibody
  • RAB3IP/Rabin8 antibody

RAB3IP/Rabin8 antibody

Cat.#: 114448

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    RAB3IP/Rabin8 antibody
  • Documents
  • Description
    RAB3IP/Rabin8 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human pancreas cancer tissue, human pancreas tissue. Positive IP detected in mouse lung tissue. Positive WB detected in human brain tissue, human heart tissue, mouse lung tissue. Observed molecular weight by Western-blot: 56 kDa
  • Tested applications
    ELISA, WB, IHC, IF, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    FLJ14660 antibody; FLJ22548 antibody; Rab 3A interacting protein antibody; Rab3A interacting protein antibody; RAB3IP antibody; Rabin 3 antibody; RABIN3 antibody; Rabin8 antibody; SSX2 interacting protein antibody
  • Isotype
    IgG
  • Preparation
    This antibody was obtained by immunization of RAB3IP/Rabin8 recombinant protein (Accession Number: BC015548). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:1000-1:10000

    IP: 1:500-1:5000

    IHC: 1:20-1:200

    IF: 1:10-1:100

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114448(RABIN8 antibody) at dilution of 1:2000

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114448(RABIN8 antibody) at dilution of 1:2000

    IP Result of anti-RABIN8 (IP:Catalog No:114448, 3ug; Detection:Catalog No:114448 1:1000) with mouse lung tissue lysate 4500ug.

    IP Result of anti-RABIN8 (IP:Catalog No:114448, 3ug; Detection:Catalog No:114448 1:1000) with mouse lung tissue lysate 4500ug.

    Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:114448(RABIN8 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:114448(RABIN8 antibody) at dilution of 1:50 (under 10x lens)

    Immunofluorescent analysis of HepG2 cells, using RAB3IP antibody Catalog No:114448 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

    Immunofluorescent analysis of HepG2 cells, using RAB3IP antibody Catalog No:114448 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

  • Background
    RAB3IP represents RAB3A interacting protein (rabin3)
  • References
    • Bryant DM, Datta A, Rodríguez-Fraticelli AE, Peränen J, Martín-Belmonte F, Mostov KE. A molecular network for de novo generation of the apical surface and lumen. Nature cell biology. 12(11):1035-45. 2010.
    • Parkhitko CA, Favorova CO, Henske EP. Rabin8 Protein Interacts with GTPase Rheb and Inhibits Phosphorylation of Ser235/Ser236 in Small Ribosomal Subunit Protein S6. Acta naturae. 3(3):71-6. 2011.
    • Demir K, Kirsch N, Beretta CA. RAB8B is required for activity and caveolar endocytosis of LRP6. Cell reports. 4(6):1224-34. 2013.
    • Burke MC, Li FQ, Cyge B. Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation. The Journal of cell biology. 207(1):123-37. 2014.
    • Zhang B, Zhang T, Wang G. GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis. PLoS biology. 13(4):e1002129. 2015.
    • Ultanir SK, Hertz NT, Li G. Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Neuron. 73(6):1127-42. 2012.
    • Lai YC, Kondapalli C, Lehneck R. Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1. The EMBO journal. 34(22):2840-61. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"