Recombinant PSG1 protein (His tag)

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• Material Safety Data Sheets (MSDS)

Recombinant Human Pregnancy-specific beta-1-glycoprotein 1 (PSG1) Fragment (aa 35-419) is a high-purity protein designed for functional studies. This fragment encompasses the Ig-like V-type and three Ig-like C2-type domains, making it an ideal tool for investigating domain-specific interactions and immunological roles in pregnancy and cancer research.

Pregnancy-specific beta-1-glycoprotein 1 (PSG1), also known as CD66f, is a secreted glycoprotein belonging to the carcinoembryonic antigen (CEA) family. As a pregnancy-specific protein, it is abundantly expressed in the placenta and plays critical roles in maternal-fetal immunomodulation, potentially regulating immune tolerance during gestation. Its classification as a CD66 antigen family member suggests involvement in cell adhesion and signaling processes. The secreted nature of PSG1, as indicated by its subcellular location, allows it to function in extracellular environments, where it may interact with immune cells and other molecular partners. PSG1 has also been studied in oncological contexts due to its expression in certain fetal and tumor tissues, highlighting its dual significance in reproductive biology and cancer immunology.