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  • Prothymosin alpha antibody

Prothymosin alpha antibody

Cat.#: 114223

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Product Information

  • Product Name
    Prothymosin alpha antibody
  • Documents
  • Description
    Prothymosin alpha Rabbit Polyclonal antibody. Positive IHC detected in human lymphoma tissue.
  • Tested applications
    ELISA, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    Prothymosin alpha antibody; prothymosin antibody; alpha antibody; PTMA antibody; TMSA antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Prothymosin alpha recombinant protein (Accession Number: BC003510). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    IHC: 1:20-1:200

  • Validations

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:114223(PTMA antibody) at dilution of 1:100 (under 25x lens)

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:114223(PTMA antibody) at dilution of 1:100 (under 25x lens)

  • Background
    Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"