PRMT5 antibody

PRMT5 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PRMT5 Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue, human brain tissue, human heart tissue, human kidney tissue, human lung cancer tissue, human lung tissue, human ovary tissue, human ovary tumor tissue, human placenta tissue, human spleen tissue. Positive WB detected in HepG2 cells, Jurkat cells, Raji cells. Observed molecular weight by Western-blot: 72 kDa

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

72 kDa ICln binding protein antibody; HRMT1L5 antibody; IBP72 antibody; Jak binding protein 1 antibody; JBP1 antibody; PRMT5 antibody; SKB1 antibody; SKB1 homolog antibody; SKB1Hs antibody

Rabbit IgG

This antibody was obtained by immunization of PRMT5 recombinant protein (Accession Number: NM_006109). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

PRMT5 is a Type II enzyme that catalyzes arginine monomethylation and symmetric dimethylation (Rme1 and Rme2s). The many targets of PRMT5 include ribosomal proteins, the histone chaperone nucleoplasmin, p53, and histones. PRMT5 is frequently observed in a complex with the cofactor, methylosome protein 50 (MEP50), which is required for PRMT5 activity. PRMT5 is upregulated in several human malignancies, including lymphomas, lung cancer, breast cancer and colorectal cancer.