Prenylagaramide B peptide

Prenylagaramide B peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

cyclo(-YLYPINP-)

cyclo(-Ptyr-Leu-Tyr-Pro-Ile-Asn-Pro-)

7

95.5%

C₄₉H₆₈N₈O₁₀

929.11

Synthetic

Powder

The source of Prenylagaramide B is cyanobavterium / blue-gren algae: Oscillatoria agardhii / Planktothrix agardhii).
Prenylagaramide B is a cyclic peptide which can be isolated from the cultured cyanobacteria Oscillatoria agardhii (NIES-596). The structure contains a rare O-prenyltyrosine (Ptyr) unit, was established as cyclo(-Ptyr1-Leu2-Tyr3-Pro4-Ile5-Asn6-Pro7-) by spectroscopic analysis and chemical degradation.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Murakami M, Itou Y, Ishida K, Shin HJ. Prenylagaramides A and B, new cyclic peptides from two strains of oscillatoria agardhii. J Nat Prod. 1999;62(5):752-5.
• Welker M, Christiansen G, von Döhren H. Diversity of coexisting Planktothrix (cyanobacteria) chemotypes deduced by mass spectral analysis of microystins and other oligopeptides. Arch Microbiol. 2004 Oct;182(4):288-98.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.