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Recombinant PLGF protein (His tag)

Recombinant PLGF protein (His tag)

Cat.#: 544652

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Special Price 294.7 USD

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Product Information

  • Product Name
    Recombinant PLGF protein (His tag)
  • Documents
  • Description

    Recombinant Human Placenta Growth Factor (PlGF) Fragment (19-134) is a highly pure, stable protein fragment ideal for angiogenesis research, endothelial cell studies, and structural biology applications. This 116-amino acid fragment maintains key functional properties while offering enhanced solubility and stability for experimental use.

    Placenta Growth Factor (PlGF), encoded by the PGF gene, is a crucial growth factor active in angiogenesis and endothelial cell development. It stimulates proliferation and migration of endothelial cells by binding to the FLT1/VEGFR-1 receptor. The PlGF-2 isoform additionally binds to NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. PlGF also promotes tumor cell growth and is naturally secreted, with the PlGF-2 isoform remaining cell-attached until released by heparin. This protein plays significant roles in vascular development and pathological conditions involving angiogenesis.

  • Protein name
    Placenta growth factor
  • Uniprot ID
    P49763
  • Gene Name
    PGF; PGFL; PLGF
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 19-134 aa (P49763) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 14.58 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 15 kDa band.
  • Purity
    >85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"