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Product Name
Rat PDGFRA/CD140a (His Tag) recombinant protein
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Description
Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
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Protein name
Platelet-derived growth factor receptor alpha
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Protein short names
MGC74795; PDGFR2; PDGFRA; RHEPDGFRA; CD140A; AI115593; PDGFR-2
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Uniprot ID
P20786
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Gene Name
Pdgfra; rCG_57147
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat PDGFRA (NP_036934.1) (Met1-Glu523) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat PDGFRA comprises 511 amino acids and predicts a molecular mass of 57.6 kDa. The apparent molecular mass of the recombinant protein is approximately 70-110 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Rat PDGFRa / CD140a Protein (His Tag) SDS-PAGE
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