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  • PIK3IP1 antibody
  • PIK3IP1 antibody

PIK3IP1 antibody

Cat.#: 113904

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Special Price 239.0 USD

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Product Information

  • Product Name
    PIK3IP1 antibody
  • Documents
  • Description
    PIK3IP1 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, HepG2 cells, mouse liver tissue. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 37 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    HGFL antibody; hHGFL(S) antibody; PIK3IP1 antibody
  • Isotype
    IgG
  • Preparation
    This antibody was obtained by immunization of PIK3IP1 recombinant protein (Accession Number: BC011049). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:113904(PIK3IP1 antibody) at dilution of 1:500

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:113904(PIK3IP1 antibody) at dilution of 1:500

    IP Result of anti-PIK3IP1 (IP:Catalog No:113904, 4ug; Detection:Catalog No:113904 1:500) with HeLa cells lysate 3200ug.

    IP Result of anti-PIK3IP1 (IP:Catalog No:113904, 4ug; Detection:Catalog No:113904 1:500) with HeLa cells lysate 3200ug.

  • Background
    PIK3IP1(Phosphoinositide-3-kinase-interacting protein 1) is also named as HGFL. The class IA phosphoinositol-3-kinases (PI3Ks) regulate important cellular processes such as proliferation, growth, survival, motility and metabolism. PIK3IP1 is a transmembrane protein that possesses a region in its intracellular domain that shares homology with the p85 regulatory subunit of PI3K(PMID:18632611). It has 4 isoforms produced by alternative splicing. It also has a signal peptide and two glycosylation sites.
  • References
    • Song HK, Kim J, Lee JS. Pik3ip1 modulates cardiac hypertrophy by inhibiting PI3K pathway. PloS one. 10(3):e0122251. 2015.
    • Wong CC, Martincorena I, Rust AG. Inactivating CUX1 mutations promote tumorigenesis. Nature genetics. 46(1):33-8. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"