Phoenixin-14 amide (Human) peptide

Phoenixin-14 amide (Human) peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

H-DVQPPGLKVWSDPF-NH2

H-Asp-Val-Gln-Pro-Pro-Gly-Leu-Lys-Val-Trp-Ser-Asp-Pro-Phe-NH2

14

98.74%

C₇₅H₁₁₀N₁₈O₂₀

1583.78

Synthetic

Powder

PNX-14 is a novel neuropeptide, protecting human brain vascular endothelial cells against oxygen-glucose deprivation/reoxygenation (OGD/R)-induced inflammation and permeability, significantly ameliorating HFD-induced obesity and fatty liver, regulating pituitary gonadotropin secretion by modulating the expression of the GnRH receptor. Recent studies indicate PNX-14 is a neuropeptide with potential anti-inflammatory effects in the gastrointestinal tract.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Zandeh-Rahimi Y, Panahi N, Hesaraki S, Shirazi-Beheshtiha SH. Protective Effects of Phoenixin-14 Peptide in the Indomethacin-Induced Duodenal Ulcer: An Experimental Study. Int J Pept Res Ther. 2022;28(1):43. doi: 10.1007/s10989-021-10314-9. Epub 2022 Jan 3. PMID: 35002587; PMCID: PMC8722415.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.