pGL4.23[luc2/minP] (GGG-NH₂) amide

pGL4.23[luc2/minP] (GGG-NH₂) amide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

GGG-NH2

Gly-Gly-Gly-NH2

3

95.6%

C₆H₁₂N₄O₃

188.187

Synthetic

Powder

pGL4.23[luc2/minP], GGG-NH₂​ is a tripeptide composed of three glycines (Gly-Gly-Gly) with a C-terminal amide​ (–NH₂ replaces –COOH). It's often used as a flexible linker/spacer in peptide synthesis, PROTACs, or biotinylation substrates (e.g., luc2/minP recognizes GGG-containing tags). The amide blocks C-terminal charge and prevents exopeptidase trimming.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.