PEPD antibody

PEPD antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PEPD Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, HepG2 cells, MDA-MB-453s cells, mouse skin tissue. Positive IHC detected in human lung cancer tissue. Observed molecular weight by Western-blot: 55 kDa

ELISA, WB, IHC

Human, Mouse; other species not tested.

Imidodipeptidase antibody; PEPD antibody; peptidase D antibody; PRD antibody; PROLIDASE antibody; Proline dipeptidase antibody; X Pro dipeptidase antibody; Xaa Pro dipeptidase antibody

Rabbit IgG

This antibody was obtained by immunization of PEPD recombinant protein (Accession Number: NM_000285). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

PEPD, also named as PRD, Prolidase, X-Pro dipeptidase, Imidodipeptidase, Peptidase D and Proline dipeptidase, belongs to the peptidase M24B family and Eukaryotic-type prolidase subfamily. PEPD splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. It plays an important role in collagen metabolism because the high level of iminoacids in collagen. Defects in PEPD are a cause of prolidase deficiency (PD). PEPD is considered as the most promising candidate genes for altering AAA risk, based on gene function, association evidence, gene expression, and protein expression.(PMID:21247474)

• Lillvis JH, Kyo Y, Tromp G. Analysis of positional candidate genes in the AAA1 susceptibility locus for abdominal aortic aneurysms on chromosome 19. BMC medical genetics. 12:14. 2011.