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Product Name
Human PTH / PTH1 / Parathyroid Hormone (Fc Tag) recombinant protein
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Description
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
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Protein name
Parathyroid hormone
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Protein short names
PARATHYROID HORMONE 1; PTHP; PARATHORMONE; PARATHYRIN
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Uniprot ID
P01270
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Gene Name
PTH
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human PTH (P01270) (Ser32-Gln115) was expressed,with the fused Fc region of human IgG1 at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PTH/Fc is a disulfide-linked homodimer. The reduced monomer comprises 344 amino acids and has a predicted molecular mass of 37.9 kDa. The apparent molecular mass of the protein is approximately 40 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human PTH / PTH1 / Parathyroid Hormone Protein (Fc Tag) SDS-PAGE
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"