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Product Name
Mouse OSMR/IL-31RB (His Tag) recombinant protein
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Description
Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events (By similarity).
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Protein name
Oncostatin-M-specific receptor subunit beta
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Protein short names
MGC150627; IL-31R SUBUNIT BETA; MGC75127; OSMR; IL-31RB; MGC150626; PLCA1; OSMRB; IL-31R-BETA
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Uniprot ID
O70458
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Gene Name
Osmr; Osmrb
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse OSMR (O70458-1) extracellular domain (Met 1-Leu 738) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse OSMR consists of 726 amino acids and has a predicted molecular mass of 83.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmOSMR is approximately 120-130 kDa due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Mouse OSMR / IL-31RB Protein (His Tag) SDS-PAGE
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