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  • NVL antibody
  • NVL antibody

NVL antibody

Cat.#: 113449

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Special Price 239.0 USD

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Product Information

  • Product Name
    NVL antibody
  • Documents
  • Description
    NVL Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive WB detected in mouse lung tissue, mouse kidney tissue, mouse thymus tissue. Observed molecular weight by Western-blot: 95kd
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    nuclear VCP like antibody; Nuclear VCP like protein antibody; NVL antibody; NVLp antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of NVL recombinant protein (Accession Number: BC012105). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IF: 1:10-1:100

  • Validations

    mouse lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:113449(NVL antibody) at dilution of 1:600

    mouse lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:113449(NVL antibody) at dilution of 1:600

    Immunofluorescent analysis of HepG2 cells using Catalog No:113449(NVL Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG

    Immunofluorescent analysis of HepG2 cells using Catalog No:113449(NVL Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG

  • Background
    NVL(nuclear VCP-like) belongs to the AAA ATPase family and may facilitate the dissociation and recycling of nucleolin, thereby promoting efficient ribosome biogenesis. It acts as an ATP-dependent zinc metallopeptidase. This protein has 5 isoforms produced by alternative splicing.
  • References
    • Yun C, Wang Y, Mukhopadhyay D. Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. The Journal of cell biology. 183(4):589-95. 2008.
  • cDNA Clones

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"