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Product Name
Recombinant NUDC protein (His tag)
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Description
Recombinant Human Nuclear migration protein nudC (NUDC) Fragment (aa 154-331) is a high-purity protein designed to encompass the conserved structural domain (CS domain, aa 167-258). This fragment serves as an essential tool for investigating specific domain functions in neurogenesis, neuronal migration, and mitotic processes, offering researchers a targeted reagent for mechanistic studies.
The full-length Nuclear migration protein nudC (NUDC) in Homo sapiens plays critical roles in neurogenesis and neuronal migration. It is essential for proper mitotic spindle formation, chromosome separation during mitosis, cytokinesis, and cell proliferation. The protein localizes to the cytoplasm, cytoskeleton, mitotic spindle, midbody, and nucleus, often associating with tubulin and dynein near the microtubule organizing center. Its distribution shifts during cell migration, highlighting its dynamic involvement in cellular structure and division processes.
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Protein name
Nuclear migration protein nudC
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Uniprot ID
Q9Y266
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Gene Name
NUDC
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 154-331 aa (Q9Y266) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 22.32 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 24 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"