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  • NR2C1 antibody
  • NR2C1 antibody
  • NR2C1 antibody

NR2C1 antibody

Cat.#: 113236

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Special Price 239.0 USD

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Product Information

  • Product Name
    NR2C1 antibody
  • Documents
  • Description
    NR2C1 Rabbit Polyclonal antibody. Positive WB detected in SH-SY5Y cells, PC-3 cells. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 52kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    NR2C1 antibody; Orphan nuclear receptor TR2 antibody; Testicular receptor 2 antibody; TR2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of NR2C1 recombinant protein (Accession Number: BC040141). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:113236(NR2C1 antibody) at dilution of 1:500

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:113236(NR2C1 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:113236(NR2C1 antibody) at dilution of 1:50 (under 10x lens). Heat mediated antigen retrieved with Citric acid buffer, pH6.0

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:113236(NR2C1 antibody) at dilution of 1:50 (under 10x lens). Heat mediated antigen retrieved with Citric acid buffer, pH6.0

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:113236(NR2C1 antibody) at dilution of 1:50 (under 40x lens). Heat mediated antigen retrieved with Citric acid buffer, pH6.0

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:113236(NR2C1 antibody) at dilution of 1:50 (under 40x lens). Heat mediated antigen retrieved with Citric acid buffer, pH6.0

  • Background
    Nuclear receptor subfamily 2 group C member 1 (NR2C1), also known as Orphan nuclear receptor TR2, is a member of the steroid/thyroid hormone receptor superfamily that controls a variety of processes, including growth, differentiation and development. TR2 is known to bind to regulatory elements of the erythropoietin gene, the muscle-specific aldolase A gene and the CNTF-15 gene. In addition to TR2, a related orphan receptor, designated TR4, has been identified. TR4 forms heterodimers with TR2, which are thought to be involved in neurogenesis and germ cell development. TR2 is known to be downregulated by both p53 and ionizing radiation, and it may play a role in linking p53 to members of the steroid recepr family.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"