NR2C1 Rabbit Polyclonal antibody. Positive WB detected in SH-SY5Y cells, PC-3 cells. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 52kd
ELISA, WB, IHC
Human,Mouse,Rat; other species not tested.
NR2C1 antibody; Orphan nuclear receptor TR2 antibody; Testicular receptor 2 antibody; TR2 antibody
This antibody was obtained by immunization of NR2C1 recombinant protein (Accession Number: BC040141). Purification method: Antigen affinity purified.
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20℃. DO NOT ALIQUOT
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:113236(NR2C1 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:113236(NR2C1 antibody) at dilution of 1:50 (under 10x lens). Heat mediated antigen retrieved with Citric acid buffer, pH6.0
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:113236(NR2C1 antibody) at dilution of 1:50 (under 40x lens). Heat mediated antigen retrieved with Citric acid buffer, pH6.0
Nuclear receptor subfamily 2 group C member 1 (NR2C1), also known as Orphan nuclear receptor TR2, is a member of the steroid/thyroid hormone receptor superfamily that controls a variety of processes, including growth, differentiation and development. TR2 is known to bind to regulatory elements of the erythropoietin gene, the muscle-specific aldolase A gene and the CNTF-15 gene. In addition to TR2, a related orphan receptor, designated TR4, has been identified. TR4 forms heterodimers with TR2, which are thought to be involved in neurogenesis and germ cell development. TR2 is known to be downregulated by both p53 and ionizing radiation, and it may play a role in linking p53 to members of the steroid recepr family.
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