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Product Name
Human Neuroserpin/SerpinI1 (His Tag) recombinant protein
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Description
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
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Protein name
Neuroserpin
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Protein short names
PI12; NS; NEUROSERPIN; DKFZP781N13156; SPI17; SERPINI1; AI837402; PI-12
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Uniprot ID
Q99574
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Gene Name
SERPINI1; PI12
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human SERPINI1 (NP_005016.1) (Met 1-Leu 410) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The secreted recombinant human SERPINI1 consists of 405 amino acids after removal of the signal peptide and has a calculated molecular mass of 46 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh SERPINI1 is approximately 50-55 kDa due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human SerpinI1 / Neuroserpin Protein (His Tag) SDS-PAGE
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