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  • Mouse Crlf2/Crlm2/Tpte2/Tslpr (His tag) recombinant protein

Mouse Crlf2/Crlm2/Tpte2/Tslpr (His tag) recombinant protein

Cat.#: 518057

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Product Information

  • Product Name
    Mouse Crlf2/Crlm2/Tpte2/Tslpr (His tag) recombinant protein
  • Documents
  • Description
    The cytokine thymic stromal lymphopoietin receptor (TSLPR) is consisting of a common γ receptor–like chain (TSLPR-γ) and a common interleukin 7 (IL-7) Rα chain that belongs to the type 1 cytokine receptor family. Transfection of TSLPR cDNA result in only low affinity binding, while cotransfection of the IL-7Rα chain cDNA shows high affinity binding. TSLP and TSLPR play a critical role in the initiation of allergic diseases in mice. The TSLP R cDNA encodes a transmembrane receptor containing 370 amino acids (aa) with two potential N-linked glycosylation sites and a cytoplasmic domain of 104 aa including a single tyrosine residue. TSLPR can mediate signaling of the signal transducer and activator of transcription 5 (Stat5) by TSLP. TSLP R is broadly expressed in the immune and hematopoietic cells, particularly in hematopoietic progenitors and myeloid cells.
  • Protein name
    cytokine receptor-like factor 2(Crlf2)
  • Protein short names
    Crlm2; Tpte2; Tslpr
  • Uniprot ID
    Q8CII9
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Crlf2/Crlm2/Tpte2/Tslpr Ala20-Leu233 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Crlf2/Crlm2/Tpte2/Tslpr (His tag) recombinant protein

    Mouse Crlf2/Crlm2/Tpte2/Tslpr (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"