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Product Name
Mouse Cd160/mCG_14869 (His tag) recombinant protein
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Description
CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and smal lintestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.
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Protein name
CD160 antigen(Cd160)
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Protein short names
mCG_14869
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Uniprot ID
Q8VC80
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Cd160/mCG_14869 Gly28-Ser160 is expressed with a 6His tag at the C-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Cd160/mCG_14869 (His tag) recombinant protein
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