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Product Name
Mouse CANX recombinant protein (C-His)
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Description
Calnexin is a calcium-binding protein that belongs to the calreticulin family. It interacts with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
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Protein name
Calnexin
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Protein short names
1110069N15Rik,AI988026,Cnx,D11Ertd153e
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Uniprot ID
P35564
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Gene Name
Calnexin
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Canx (NP_031623.1) (Met1-Pro482) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Canx consists of 473 amino acids and predicts a molecular mass of 53.9 kDa.
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Purity
> 90 % as determined by SDS-PAGE.
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Validations
Mouse Calnexin / CANX Protein 15525
Mouse Calnexin / CANX Protein (His Tag)
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