Mouse CaM Kinase 4/CaMKIV recombinant protein

Mouse CaM Kinase 4/CaMKIV recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Ca²⁺/ calmodulin-dependent protein kinase 4 (CAMK?) belongs to the serine/threonine protein kinase family, and to the Ca²⁺/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme implicated in the phophoinositide amplification cascade. Ca²⁺/calmodulin dependent protein kinase (CAMK) can be activated by the introcellular increased Ca²⁺ and then apt to combine with the target protein. Ca²⁺/ calmodulin-dependent protein kinase 4 (CAMK?) is a multifunctional CaM-dependent kinase protein with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. All of the isforms of this family, including myosin light chain kinase, phosphorylase kinase, CaMK1, CaMK? and CaMK? have EF-hand structure.

Calcium/calmodulin-dependent protein kinase type IV

CAMK IV; AI666733; CAMKIV; D18BWG0362E; CAMK-GR; A430110E23RIK; CAMKIV/GR; CAMK; CAMK4; IV; MGC36771

P08414

Camk4

Baculovirus-Insect Cells

A DNA sequence encoding the mouse CAMK4(P08414) (Met1-Tyr469) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.

Mouse

The recombinant mouse CAMK4 consists of 471 amino acids and predicts a molecular mass of 52.7 KDa. It migrates as an approximately 55 KDa band in SDS-PAGE under reducing conditions.

> 95 % as determined by SDS-PAGE

Kinase activity untested