Mouse Angptl4/Farp/Fiaf/Ng27 (Fc tag) recombinant protein

Mouse Angptl4/Farp/Fiaf/Ng27 (Fc tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

angiopoietin-like 4(Angptl4)

Farp; Fiaf; Ng27

Q9Z1P8

Human Cells

A DNA sequence encoding the Mouse Angptl4/Farp/Fiaf/Ng27 Lys167-Ser410 is expressed with a Fc tag at the C-terminus.

Mouse

>95% as determined by SDS-PAGE.