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Product Name
Recombinant MOM4 protein (His tag)
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Description
Recombinant Mitogen-activated protein kinase kinase kinase mom-4 (EC 2.7.11.25) fragment (residues 40-326) from Caenorhabditis elegans, encompassing the complete Protein kinase domain. This high-purity fragment is an essential tool for investigating Wnt signaling mechanisms, mesodermal cell fate specification, and kinase activity in developmental biology research.
The full-length Mitogen-activated protein kinase kinase kinase mom-4 is a critical component of the Wnt signaling pathway in Caenorhabditis elegans, playing a fundamental role in early embryonic development. It is essential for specifying mesodermal cell fate and functions by stimulating wrm-1/lit-1-dependent phosphorylation of pop-1, while also contributing to the initial nuclear accumulation of wrm-1. These activities underscore its importance in cell signaling and developmental processes, making it a key target for studies in molecular and cellular biology.
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Protein name
Mitogen-activated protein kinase kinase kinase mom-4
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Uniprot ID
Q9XTC6
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Gene Name
mom-4
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 40-326 aa (Q9XTC6) were fused with 6His tag.
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Protein Species
Caenorhabditis elegans
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Molecular weight
Predictes a molecular mass of 34.84 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 35 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"