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Recombinant MMP8 protein (His tag)

Recombinant MMP8 protein (His tag)

Cat.#: 546850

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Special Price 294.7 USD

Availability: 3-4 weeks
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Product Information

  • Product Name
    Recombinant MMP8 protein (His tag)
  • Documents
  • Description

    This product features a recombinant fragment of human Neutrophil collagenase (Matrix metalloproteinase-8, MMP-8), encompassing residues 101-467. This stable and soluble fragment is ideal for structural studies and biochemical assays investigating collagen degradation mechanisms.

    Neutrophil collagenase (MMP-8), encoded by the MMP8 gene, is a matrix metalloproteinase that specifically degrades fibrillar collagens, including types I, II, and III. It is primarily stored in cytoplasmic granules and is secreted into the extracellular space and matrix, where it plays a critical role in tissue remodeling, inflammation, and wound healing processes.

  • Protein name
    Neutrophil collagenase
  • Uniprot ID
    P22894
  • Gene Name
    MMP8; CLG1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 101-467 aa (P22894) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 43.60 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 44 kDa band.
  • Purity
    >90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"